Bioresponsive nanosensors in medical imaging.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19846442.
- Also identified by DOI 10.1098/rsif.2009.0336.focus and PMC identifier 2843987.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Superparamagnetic iron oxide nanoparticles have been established as sensitive probes for magnetic resonance imaging (MRI). While the majority of specific nanosensors are based on sterically stabilized iron oxide particles, the focus of this review is on the use of very small iron oxide particles (VSOPs) that are electrostatically stabilized by an anionic citrate acid shell. We used VSOPs to develop target-specific as well as protease-activatable nanosensors for molecular MRI.
Medical subject headings
- Diagnostic Imaging
- Ferric Compounds
- Magnetic Resonance Imaging
- Models, Molecular
- Nanostructures