The enigmatic parietal epithelial cell is finally getting noticed: a review.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19847153.
- Also identified by DOI 10.1038/ki.2009.386 and PMC identifier 3708665.
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Abstract
Although the normal glomerulus comprises four resident cell types, least is known about the parietal epithelial cells (PECs). This comprehensive review addresses the cellular origin of PECs, discusses the normal structure and protein makeup of PECs, describes PEC function, and defines the responses to injury in disease and how these events lead to clinical events. The data show that PECs have unique properties and that new functions are being recognized such as their role in differentiating into podocytes during disease.
Medical subject headings
- Kidney Glomerulus