Ewing's sarcoma. Prognostic factors, disease control, and the reemerging role of surgical treatment.

O'Connor, M I; Pritchard, D J · Clin Orthop Relat Res · 1991

review · Level V

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Abstract

Advances in the treatment of Ewing's sarcoma have been dramatic. Present treatment protocols control local disease by radiotherapy, surgery, or both; systemic spread is limited by aggressive multiagent chemotherapy. In patients with localized osseous Ewing's sarcoma, five-year survival rates now range from 54% to an estimated 74%. With late relapse not uncommon, control of the primary lesion is critical to long-term survival. Several studies now show improved local control and possibly improved survival of patients with surgical treatment of primary osseous Ewing's sarcoma.

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