T cell dynamics and the response to HAART in a cohort of HIV-1-infected elite suppressors.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 19857162.
- Also identified by DOI 10.1086/648081 and PMC identifier 2783537.
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Abstract
Elite controllers or suppressors are untreated human immunodeficiency virus type 1 (HIV-1)-infected patients who maintain undetectable viral loads. In this study, we show that most elite suppressors do not experience significant changes in T cell counts over a 10-year period. Interestingly, treatment of an elite suppressor with highly active antiretroviral therapy (HAART) led to a marked decrease in immune activation.
Medical subject headings
- Antiviral Agents
- HIV Infections
- T-Lymphocytes