Free fatty acids do not influence the concentrations of free steroid hormones in serum under physiological conditions.
basic_science · Level V
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- Record sourced from PubMed, PMID 1986012.
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Abstract
In several recent studies it has been suggested that FFA may influence the concentrations of unbound steroid hormones in serum, but the experimental design of these studies has been questioned. We have reexamined the effects of oleic acid on the unbound concentrations of several steroid hormones in serum, including cortisol, testosterone, and estradiol. The results demonstrate that under physiological conditions, oleic acid does not affect the unbound concentrations of these hormones when assays are carried out with whole serum.
Medical subject headings
- Estradiol
- Hydrocortisone
- Oleic Acids
- Testosterone