Methsuximide for intractable childhood seizures.
case_series · Level IV
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- Record sourced from PubMed, PMID 1987529.
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Abstract
Methsuximide was added to the therapeutic regimens of 25 children with intractable epilepsy. In 15 patients the drug was well tolerated and resulted in a 50% or greater reduction in seizure frequency. No serious or irreversible adverse effects were seen. Methsuximide is frequently overlooked and may be an effective adjunctive antiepileptic for children with intractable seizures.
Medical subject headings
- Anticonvulsants
- Epilepsy
- Succinimides