Bone marrow necrosis in leukemic-phase follicular lymphoma.
case_report · Level V
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Abstract
Bone marrow necrosis has been regarded as a rare entity in specimens obtained from living patients and has been associated with a poor prognosis. It is most commonly found in patients with neoplastic disorders, severe infections, and sickle cell anemia. We present an unusual case of a small-cleaved type follicular lymphoma associated with bone marrow necrosis and a leukemic phase occurring in a 55-year-old woman. Specimens were studied by morphologic, immunohistochemical, cytogenetic, and DNA hybridization techniques.
Medical subject headings
- Bone Marrow Diseases
- Leukemia
- Lymphoma, Follicular