Tetherin is as tetherin does.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19879831.
- Also identified by DOI 10.1016/j.cell.2009.10.011.
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Abstract
Tetherin is a cellular restriction factor that inhibits the release of HIV and other enveloped viruses from host cells. A paper from Perez-Caballero et al. (2009) in this issue of Cell clarifies how this factor works. The authors show that the aptly named tetherin directly tethers viral particles to the plasma membrane.
Medical subject headings
- Antigens, CD
- Membrane Glycoproteins
- Virion