How to drive your helicase in a straight line.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19879832.
- Also identified by DOI 10.1016/j.cell.2009.10.016.
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Abstract
Helicases are molecular motors that move along and remodel DNA, RNA, and associated protein complexes. Helicases are often directional. By analyzing crystal structures in complexes with RNA and ATP analogs, Thomsen and Berger (2009) now elucidate the molecular basis for unidirectional motion by the hexameric RNA helicase Rho.
Medical subject headings
- DNA Helicases
- Escherichia coli