MAP-ping unconventional protein-DNA interactions.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19879834.
- Also identified by DOI 10.1016/j.cell.2009.10.007.
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Abstract
Control of gene expression depends on a myriad of protein-DNA interactions, and the number of proteins involved just got larger. In this issue, Hu et al. (2009) identify hundreds of human proteins that bind to DNA, including many surprises such as the protein kinase ERK2 (MAPK1) that now appears to control gene expression directly.
Medical subject headings
- DNA-Binding Proteins
- Mitogen-Activated Protein Kinase 1