Pseudophosphatases: grab and hold on.

Tonks, Nicholas K · Cell · 2009

basic_science · Level V

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Abstract

Catalytically inactive pseudophosphatases are able to signal in the absence of enzymatic activity. Analyzing the oocyte-to-zygote transition in the worm, Cheng et al. (2009) and Parry et al. (2009) now show how two pseudophosphatases, EGG-4 and EGG-5, can regulate signaling by the DYRK family kinase MBK-2.

Medical subject headings