Polycystins under pressure.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19879836.
- Also identified by DOI 10.1016/j.cell.2009.10.009.
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Abstract
All cells detect mechanical signals, but the underlying molecular mechanisms are unclear. In this issue of Cell, Sharif-Naeini et al. (2009) show that a candidate mechanosensing channel, TRPP2 (PKD2), unexpectedly acts as an inhibitor of a still-elusive stretch-activated cation channel in vascular smooth muscle cells.
Medical subject headings
- Muscle, Smooth, Vascular
- TRPP Cation Channels