Bisphosphonate-related osteonecrosis of the jaw: the role of actinomyces.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19886792.
- Also identified by DOI 10.1086/648075.
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Abstract
The etiology of bisphosphonate-related osteonecrosis of the jaw is unknown but was initially postulated to be mediated by bisphosphonate accumulation within the jaws, resulting in avascular necrosis. Bisphosphonates may not be the primary cause. Actinomyces are an underrecognized agent in pathogenesis, and timely actinomycosis-specific treatment may improve outcome.
Medical subject headings
- Actinomyces
- Bone Density Conservation Agents
- Diphosphonates
- Jaw Diseases
- Osteonecrosis