VEGF: a surrogate marker for peripheral vascular disease.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 19889554.
- Also identified by DOI 10.1016/j.ejvs.2009.09.025.
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Abstract
This study aims to evaluate the value of VEGF as a surrogate marker for peripheral vascular disease (PVD). Prior to treatment, serum VEGF levels were evaluated by enzyme-linked immunosorbent assay (ELISA) in 293 PVD patients. Risk factors and clinical parameters of PVD were documented. Twenty-six age-matched healthy volunteers served as controls. Serum VEGF values strongly correlated with Fontaine stages (p<0.006, stage IV vs. controls). High VEGF values prior to treatment were associated with poor outcome. Serum VEGF appears to indicate the severity of PVD and might serve as a surrogate indicator of disease severity.
Medical subject headings
- Peripheral Vascular Diseases
- Vascular Endothelial Growth Factor A