Getting knit-PI3Ky: PIK3CA mutation status to direct multimodality therapy?
Where this comes from
- Record sourced from PubMed, PMID 19903790.
- Also identified by DOI 10.1158/1078-0432.CCR-09-2305 and PMC identifier 3400141.
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Abstract
There is high morbidity associated with local recurrence of rectal cancer. However, the adjuvant therapies given to prevent such recurrences also have significant side effects and associated risks. The ability to select patients with the highest risk of recurrence and greatest therapeutic response will improve rectal cancer care.
Medical subject headings
- Mutation
- Phosphatidylinositol 3-Kinases
- Rectal Neoplasms