Understanding microRNAs in neurodegeneration.

Eacker, Stephen M; Dawson, Ted M; Dawson, Valina L · Nat Rev Neurosci · 2009

review · Level V

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Abstract

Interest in the functions of microRNAs (miRNAs) in the nervous system has recently expanded to include their roles in neurodegeneration. Investigations have begun to reveal the influence of miRNAs on both neuronal survival and the accumulation of toxic proteins that are associated with neurodegeneration, and are providing clues as to how these toxic proteins can influence miRNA expression.

Medical subject headings