Compete globally, bud locally.

Houk, Andrew R; Millius, Arthur; Weiner, Orion D · Cell · 2009

basic_science · Level V

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Abstract

How cells generate a single axis of polarity for mating, division, and movement is unknown. In this issue, Howell et al. (2009) use a synthetic biology approach to demonstrate that rapid competition for a soluble signaling component (Bem1) is essential to ensure a unique axis of polarity in budding yeast.

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