Effective desensitization to imiglucerase in a patient with type I Gaucher disease.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19914435.
- Also identified by DOI 10.1016/j.jpeds.2009.05.033.
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Abstract
We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date.
Medical subject headings
- Anaphylaxis
- Desensitization, Immunologic
- Drug Hypersensitivity
- Gaucher Disease
- Glucosylceramidase