Acquired pendular nystagmus in toluene addiction.

Maas, E F; Ashe, J; Spiegel, P; Zee, D S; Leigh, R J · Neurology · 1991

case_series · Level IV

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Abstract

We studied the ocular motor abnormalities in 4 patients chronically addicted to sniffing glue containing toluene. They showed acquired pendular nystagmus with horizontal and vertical components. One patient also showed saccadic oscillations. The pendular nystagmus may be a manifestation of a disturbance in brainstem-cerebellar connections secondary to the toxic effect of toluene on white matter.

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