Vasoactive intestinal polypeptide loses its ability to increase vaginal blood flow after menopause.

Palle, C; Bredkjaer, H E; Fahrenkrug, J; Ottesen, B · Am J Obstet Gynecol · 1991

case_control · Level III

Where this comes from

Abstract

The effect of vasoactive intestinal polypeptide on vaginal blood flow was investigated in postmenopausal women. In women who were receiving hormonal replacement therapy the vasodilatory response induced by vasoactive intestinal polypeptide was identical to that of young women, whereas in postmenopausal women who were receiving no replacement therapy, the response induced by vasoactive intestinal polypeptide was absent. Plasma levels of vasoactive intestinal polypeptide and systemic cardiovascular effects were identical in the two groups.

Medical subject headings