Expertomica Cells: analysis of cell monolayer development.

Levitner, Tomás; Timr, Stepán; Stys, Dalibor · Bioinformatics · 2010

basic_science · Level V

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Abstract

Expertomica Cells is a program for the creation and analysis of pedigree plots from time-lapse micrographs of cell monolayers. It enables recording the basic events in a cell cycle, cell neighbourhoods and spatial migration. The output is both numeric and graphical. The software helps to lower main hurdles in the manual analysis of cell monolayer development to practical limits; it reduces the operator processing time of typical experiment containing 5000 consecutive images from the usual 3 months to 3-10 h. Freely available on the web at http://www.expertomicacells.tk or http://www.expertomicacells.wu.cz. The source code is implemented in JAVA 6 and supported by Linux, Mac and MS Windows. Supplementary data available at Bioinformatics online.

Medical subject headings