Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19944484.
- Also identified by DOI 10.1016/j.jaad.2009.02.035.
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Abstract
Cutaneous T-cell lymphomas most commonly have a CD4(+) memory T-cell phenotype with relatively indolent course, but may in rare cases present with a CD8(+) cytotoxic phenotype exhibiting strikingly more aggressive clinical behavior. We present two cases of the clinically aggressive subtype of primary cutaneous epidermotropic CD8(+) cutaneous T-cell lymphoma and review the current literature, clinical behavior, and recommendations for treatment distinct from that of more common CD4(+) variants of cutaneous T-cell lymphoma.
Medical subject headings
- CD8-Positive T-Lymphocytes
- Lymphoma, T-Cell, Cutaneous
- Skin Neoplasms