RNAi: prokaryotes get in on the act.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19945373.
- Also identified by DOI 10.1016/j.cell.2009.11.018.
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Abstract
The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA.
Medical subject headings
- Pyrococcus furiosus
- RNA Interference
- RNA, Archaeal