Putting the brakes on dietary fat breakdown.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19945400.
- Also identified by DOI 10.1016/j.cmet.2009.11.004.
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Abstract
Dietary lipid digestion is critical for body fat storage control, but little is known about the regulation of genes involved in fat breakdown and absorption in the gastrointestinal tract. A Drosophila study (Sieber and Thummel, 2009 [this issue of Cell Metabolism]) now demonstrates that the orphan nuclear receptor DHR96 adjusts fat storage in flies by tuning gastric lipase expression.