Diabetes and the abdominal aortic aneurysm.
meta_analysis · Level I
Where this comes from
- Record sourced from PubMed, PMID 19948418.
- Also identified by DOI 10.1016/j.ejvs.2009.10.014.
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Abstract
The aim of this review is to delineate the association between abdominal aortic aneurysms (AAAs) and diabetes mellitus. Mechanisms for the underlying association are then discussed. A systematic review of the English-language literature using PubMed, EMBASE and Cochrane databases was undertaken up to September 2009. Studies reporting appropriate prevalence data were identified and a meta-analysis performed. Eleven studies were identified. The prevalence of diabetes mellitus in studied patients with AAA ranged from 6% to 14%. The prevalence of diabetes in control patients without AAA ranged from 17% to 36%. Pooled analysis suggested a reduced rate of diabetes amongst people with AAA compared to those without (OR 0.65, 0.60-0.70, p<0.001). Studies so far suggest a protective role for diabetes on the development of AAA. Further research is required to demarcate the underlying mechanisms for this possible association.
Medical subject headings
- Aortic Aneurysm, Abdominal
- Diabetes Complications
- Diabetes Mellitus