Miltefosine treatment of Leishmania major infection: an observational study involving Dutch military personnel returning from northern Afghanistan.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 19951107.
- Also identified by DOI 10.1086/648726.
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Abstract
In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSb(v)), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSb(v), and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients.
Medical subject headings
- Leishmania major
- Leishmaniasis, Cutaneous
- Phosphorylcholine