Infrequent replication of parvovirus B19 and erythrovirus genotypes 2 and 3 among HIV-infected patients with chronic anemia.

Ferry, Tristan; Hirschel, Bernard; Dang, Thanh; Meylan, Pascal; Delhumeau, Cécile; Rauch, Andri; Weber, Rainer; Elzi, Luigia et al. · Clin Infect Dis · 2010

cross_sectional · Level IV

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Abstract

We investigated the role that erythroviruses (parvovirus B19 and erythrovirus genotypes 2 and 3) play in the lives of immunosuppressed HIV-infected patients with chronic anemia. We screened the serum samples of 428 patients by specific ultrasensitive real-time polymerase chain reaction assay. Sixteen patients had circulating DNA, with no apparent clinical impact. Erythrovirus-associated anemia is an extremely rare event in HIV-infected patients.

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