Preview. A shore sign of reprogramming.
editorial · Level V
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- Record sourced from PubMed, PMID 19951682.
- Also identified by DOI 10.1016/j.stem.2009.11.006.
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Abstract
Recent genome-wide descriptions of CpG methylation patterns in mammalian cells identified many differentially methylated regions (DMRs) located at CpG island "shores." Feinberg, Daley, and colleagues now report in Nature Genetics that reconfiguration of these DMRs occurs during induced reprogramming (Doi et al., 2009).