Preview. Adult neurogenesis is altered by GABAergic imbalance in models of Alzheimer's disease.
editorial · Level V
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- Record sourced from PubMed, PMID 19951683.
- Also identified by DOI 10.1016/j.stem.2009.11.007.
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Abstract
Early stages of Alzheimer's disease (AD) affect hippocampal function. In this issue of Cell Stem Cell, Li et al. (2009) and Sun et al. (2009) propose abnormal GABA signaling as a trigger for impaired network plasticity in the AD hippocampus.