Preview. Stem cell transcriptional loops generate precise temporal identity.
basic_science · Level V
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- Record sourced from PubMed, PMID 19951685.
- Also identified by DOI 10.1016/j.stem.2009.11.004.
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Abstract
Neuronal diversity is generated from small pools of progenitors whose fate potential changes over time. Recently in Cell, Baumgardt et al. (2009) showed that multiple, simultaneously activated transcriptional cascades regulate the timing and specification of distinct neurons from the lineage of a single embryonic Drosophila neural stem cell.