Particle size of inhaled corticosteroids: does it matter?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19962042.
- Also identified by DOI 10.1016/j.jaci.2009.09.050.
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Abstract
A question with respect to asthma therapy revolves around the issue of whether better efficacy occurs with an ultrafine-particle inhaled corticosteroid because of better lung deposition into the distal airways. This article reviews particle size and delivery devices of different steroids, clinical outcomes of small- versus large-particle steroids, and the issue of pharmacoeconomics.
Medical subject headings
- Adrenal Cortex Hormones
- Anti-Asthmatic Agents
- Asthma
- Particle Size