Localization and quantitation of tritiated compounds in tissue sections with a gaseous detector of beta particles: comparison with film autoradiography.

Tribollet, E; Dreifuss, J J; Charpak, G; Dominik, W; Zaganidis, N · Proc Natl Acad Sci U S A · 1991

other · Level V

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Abstract

Quantitative analysis of tritium polymer standards and of brain sections labeled with tritiated vasopressin was carried out by using a gaseous detector of beta particles designed for this purpose. The gaseous detector showed major advantages compared with film autoradiography: the linearity and the large dynamic range of intensity measurements as well as the short time needed for data acquisition.

Medical subject headings