Automated high-throughput cell microsurgery on-chip.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19967110.
- Also identified by DOI 10.1039/b910703g.
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Abstract
Laser cell kill is an established tool for studying cells' roles during development and behavior, but its use has been limited due to the manual and low-throughput nature. We demonstrate here a technique combining multiplexing microfluidic manipulation of Caenorhabditis elegans and software for image processing and automation, allowing for high-throughput cell ablations.
Medical subject headings
- Caenorhabditis elegans
- Microfluidic Analytical Techniques