Apparent response of subacute sclerosing panencephalitis to intrathecal interferon alpha.
case_report · Level V
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Abstract
An 8-year-old boy with subacute sclerosing panencephalitis (SSPE) was treated with 1.0 to 3.0 x 10(6) IU human interferon alpha (IFN) by the intrathecal route weekly or fortnightly. Pronounced improvement of clinical and electroencephalographic findings were observed in a dose-dependent manner. Our patient raises hope that IFN can induce sustained remission in patients with SSPE.
Medical subject headings
- Interferon Type I
- Subacute Sclerosing Panencephalitis