Staphylococcus aureus Panton-Valentine leukocidin targets muscle tissues in a child with myositis and necrotizing fasciitis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19995216.
- Also identified by DOI 10.1086/649217.
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Abstract
The incidence of myositis has been increasing since the advent of the epidemic of community-associated methicillin-resistant Staphylococcus aureus infection, and Panton-Valentine leukocidin has been implicated as a factor contributing to more-severe muscle injury. We report a case of severe myositis accompanying septic osteomyelitis and necrotizing fasciitis caused by a Panton-Valentine leukocidin-positive S. aureus strain. Immunostaining showed strong binding of the Panton-Valentine leukocidin toxin to necrotic muscle tissues.
Medical subject headings
- Bacterial Toxins
- Exotoxins
- Fasciitis, Necrotizing
- Leukocidins
- Myositis
- Staphylococcus aureus