Switching on epigenetic therapy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20005793.
- Also identified by DOI 10.1016/j.cell.2009.11.038.
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Abstract
Reversible epigenetic changes that alter gene expression are a characteristic of many cancers and other diseases. Biotech companies are taking note and are starting to develop new drugs to reverse such pathogenic "epimutations."
Medical subject headings
- Chromatin Assembly and Disassembly
- Epigenesis, Genetic
- Neoplasms