The dangers of transcription.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20005797.
- Also identified by DOI 10.1016/j.cell.2009.11.037 and PMC identifier 6312720.
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Abstract
Transcription is obviously essential, but even a good thing can be dangerous at times. In this issue, Lin et al. (2009) provide evidence that binding of the transcription machinery may predispose genome regions to breakage and translocations that may lead to cancer.
Medical subject headings
- Gene Expression Regulation, Neoplastic
- Translocation, Genetic