A tethering complex recruits SNAREs and grabs vesicles.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20005800.
- Also identified by DOI 10.1016/j.cell.2009.11.041.
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Abstract
Protein tethers can bridge gaps between membranes. Ren et al. (2009) now provide evidence that the yeast Dsl1 complex tethers vesicles to the endoplasmic reticulum (ER) by binding ER SNARE proteins at its base and capturing vesicles using a loop region that extends 20 nm from the ER membrane.
Medical subject headings
- SNARE Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transport Vesicles
- Vesicular Transport Proteins