Determinants of kidney dysfunction: is vasopressin a new player in the arena?
Level V
Where this comes from
- Record sourced from PubMed, PMID 20010879.
- Also identified by DOI 10.1038/ki.2009.408.
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Abstract
Copeptin is a marker of endogenous vasopressin secretion. Population-based data of the PREVEND Study show that men and women with high plasma copeptin have a highly prevalent microalbuminuria in addition to the low level of hydration typical of persons with high vasopressin secretion. The association of plasma copeptin with microalbuminuria suggests that vasopressin might have a role in kidney dysfunction via effects on the permselectivity of the glomerulus and/or on tubular albumin reabsorption.
Medical subject headings
- Renal Insufficiency
- Vasopressins