45,X/46,X dic (Y) mosaicism in a phenotypic male.

Batstone, P J; Faed, M J; Jung, R T; Gosden, J · Arch Dis Child · 1991

case_report · Level V

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Abstract

Cytogenetic analysis, confirmed by in situ hybridisation studies, showed a mosaic 45,X/46,X dic (Y) (q12) karyotype in a 14 year old boy who was initially diagnosed as having Noonan's syndrome. He made an early response to recombinant growth hormone; this suggests that this treatment may improve final height.

Medical subject headings