"Smart" diblock copolymers as templates for magnetic-core gold-shell nanoparticle synthesis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20017498.
- Also identified by DOI 10.1021/nl902865v and PMC identifier 2806508.
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Abstract
We report a new strategy for synthesizing temperature-responsive gamma-Fe(2)O(3)-core/Au-shell nanoparticles (Au-mNPs) from diblock copolymer micelles. The amphiphilic diblock copolymer chains were synthesized using reversible addition-fragmentation chain-transfer (RAFT) with a thermally responsive "smart" poly(N-isopropylacrylamide) (pNIPAAm) block and an amine-containing poly(N,N-dimethylaminoethylacrylamide) (DMAEAm) block that acted as a reducing agent during gold shell formation. The Au-mNPs reversibly aggregated upon heating the solution above the transition temperature of pNIPAAm, resulting in a red-shifted localized surface plasmon resonance.
Medical subject headings
- Gold
- Metal Nanoparticles
- Micelles
- Nanotechnology