Comparison of DiaSorin and Bio-Rad test kits for the detection of hepatitis B virus total core and surface antibodies on the Bio-Rad Evolis.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 20023266.
- Also identified by DOI 10.1309/AJCPHY8P2LOIKFBE.
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Abstract
The new MONOLISA Bio-Rad kits were compared to DiaSorin kits for the detection of hepatitis B virus (HBV) total core (HBcTAb) and surface (HBsAb) antibodies on the Bio-Rad Evolis immunoanalyzer. The resolved sensitivities, specificities, positive and negative predictive values, and overall accuracy were 91%, 100%, 100%, 96%, and 97%, respectively, for HBcTAb and 99%, 95%, 96%, 99%, and 97%, respectively, for HBsAb. Whereas accuracy and reagent cost were comparable between the kits, Bio-Rad kits required less specimen volume and less instrument processing time to results than the DiaSorin kits.
Medical subject headings
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Core Antigens
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Reagent Kits, Diagnostic