Science to practice: what does MR oxygenation imaging tell us about human breast cancer hypoxia?
Level V
Where this comes from
- Record sourced from PubMed, PMID 20032129.
- Also identified by DOI 10.1148/radiol.091669.
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Abstract
The paradoxical relationship between blood oxygen level-dependent (BOLD) magnetic resonance (MR) imaging and breast cancer hypoxia challenges our current understanding of what we believe is happening to erythrocytes in tumors. The ability of air breathing R2* measurements to reflect tissue hypoxia appears to be tumor type-specific, which should prompt further exploration of this image contrast mechanism in both human and animal tumors.
Medical subject headings
- Breast Neoplasms
- Erythrocytes
- Hypoxia
- Magnetic Resonance Imaging
- Oxygen
- Tomography, Emission-Computed