T cells and dendritic cells in glomerular disease: the new glomerulotubular feedback loop.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20032960.
- Also identified by DOI 10.1038/ki.2009.489 and PMC identifier 3039448.
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Abstract
A newly described glomerulotubular feedback loop may explain the relationship between glomerular damage, epitope spreading, tubulointerstitial nephritis, proteinuria as a progression factor, and the importance of the local milieu in kidney damage. It also opens the horizons for exciting innovative approaches to therapy of both acute and chronic kidney diseases.
Medical subject headings
- Dendritic Cells
- Kidney Diseases
- Kidney Glomerulus
- Kidney Tubules
- T-Lymphocytes