Clindamycin-resistant group B Streptococcus and failure of intrapartum prophylaxis to prevent early-onset disease.

Blaschke, Anne J; Pulver, Laurie S; Korgenski, E Kent; Savitz, Lucy A; Daly, Judy A; Byington, Carrie L · J Pediatr · 2010

case_report · Level V

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Abstract

Guidelines recommend intrapartum antibiotic prophylaxis (IAP) for parturient women who have a screen positive for group B Streptococcus (GBS). Clindamycin should be used for IAP only if the maternal GBS isolate is susceptible. We report a case of clindamycin-resistant GBS disease in a newborn infant whose mother received clindamycin IAP, and we review clindamycin susceptibility testing.

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