Tumor self-seeding: bidirectional flow of tumor cells.

Leung, Cheuk T; Brugge, Joan S · Cell · 2009

basic_science · Level V

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Abstract

Circulating tumor cells are responsible for seeding metastatic growth at distant sites. Kim et al. (2009) now discover that circulating tumor cells can reinfiltrate tumors at their primary organs and promote tumor progression.

Medical subject headings