Counting single molecules in sub-nanolitre droplets.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 20066242.
- Also identified by DOI 10.1039/b917503b and PMC identifier 3000353.
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Abstract
We demonstrate single biomolecule detection and quantification within sub-nanolitre droplets through application of Cylindrical Illumination Confocal Spectroscopy (CICS) and droplet confinement within a retractable microfluidic constriction.
Medical subject headings
- DNA
- Microfluidic Analytical Techniques
- Microscopy, Confocal
- Nanostructures
- Nanotechnology
- Spectrometry, Fluorescence