Neuroglobin expression in ischemic stroke.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 20075359.
- Also identified by DOI 10.1161/STROKEAHA.109.567149 and PMC identifier 2842002.
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Abstract
We investigated whether neuroglobin, a neuronal protein that protects neurons from hypoxic-ischemic injury, is upregulated in ischemic stroke. Neuroglobin immunoreactivity was measured in brain tissue from control subjects and patients with ischemic stroke. Neuroglobin was detected in several brain areas, and its expression was increased in the cortical peri-infarct region after stroke. Ischemic stroke increases expression of the neuroprotective protein neuroglobin, suggesting neuroglobin may represent a novel target for stroke therapy.
Medical subject headings
- Brain Ischemia
- Globins
- Nerve Tissue Proteins
- Stroke