The genetics of albuminuria: from haplotype association mapping in mice to genetic causation in humans.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 20075951.
- Also identified by DOI 10.1038/ki.2009.457.
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Abstract
Genome-wide haplotype association mapping (HAM) in inbred mouse strains emerged as an efficient method for identifying novel quantitative trait loci for disease-related phenotypes. In this issue of Kidney International, Tsaih et al. present the results of the first HAM for age-related kidney damage in mice and examine the detected loci in the context of the human genome-wide association study for diabetic nephropathy.
Medical subject headings
- Albuminuria
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Quantitative Trait Loci