Hepatitis B virus infection in hemodialysis populations: progress toward prevention.

Barraclough, Katherine A; Playford, E Geoffrey · Kidney Int · 2010

editorial · Level V

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Abstract

Hemodialysis patients are at increased risk of acquiring hepatitis B virus (HBV) infection. Administration of the standard HBV vaccine is suboptimal as a means of prevention because of an impaired seroconversion response in individuals with chronic kidney disease. Surquin and colleagues describe a novel vaccine adjuvant system that increases speed of seroconversion and duration of seroprotection compared with older vaccine formulations. However, its ability to improve overall seroconversion response remains unproven.

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